# Snap8 > Research use only. Not for human or veterinary use. Supplied by Veracue Labs. - Page: https://veracuelabs.com/product/snap8 - Category: Cosmetic & Skin - Sizes and prices in USD: 10 mg at $49.49; 20 mg at $65.99 - Certificate of analysis: none posted on the page. Request one for a specific lot at https://veracuelabs.com/contact-us. - Prices are a snapshot from 2026-10-17. The product page shows the current price. ## Overview Snap8 is a synthetic octapeptide with the sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2, acetylated at the N-terminus and amidated at the C-terminus. Its reference record gives the formula C41H70N16O16S, a molecular weight of 1075.2 g/mol and CAS 868844-74-0. It is modeled on a short stretch of SNAP-25 and is easily confused with Argireline, a shorter six-residue peptide that lacks the final alanine and aspartic acid. Both the 10 mg and 20 mg vials are supplied strictly for laboratory research. ## Product Details ### What Is Snap8? Snap8 is a synthetic octapeptide, Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2, modeled on a short sequence from SNAP-25, a protein that forms part of the SNARE membrane-fusion complex. It is built in a laboratory, not isolated from a natural source. Veracue supplies it for laboratory research only. Snap8 is not a naturally occurring SNAP-25 fragment. It is a laboratory-made peptide corresponding to part of that sequence, which is why it is used as a reference material in SNARE-related assay work. ### Snap8 at a Glance Product name: Snap8 (also written Snap-8 or SNAP-8) Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (Ac-EEMQRRAD-NH2) Length: 8 amino acid residues, N-terminally acetylated and C-terminally amidated Molecular formula: C41H70N16O16S Molecular weight: 1075.2 g/mol CAS Registry Number: 868844-74-0 PubChem CID: 76283482 Available sizes: 10 mg and 20 mg vials Research designation: Research Use Only Formula, weight and CID are from the PubChem record linked to CAS 868844-74-0. That record describes the peptide as a reference structure and is not a statement about the form Veracue supplies. Some third-party listings describe an acetate salt. Salt or counterion form, purity, lot results and storage conditions are reported on each lot’s documentation and can be requested through the contact page. ### What Snap8 Is Not - Not SNAP-25 itself, and not a natural fragment isolated from it. - Not the same as Argireline, which is a shorter six-residue peptide. - Not a consumer or dietary product. - Not intended for human or veterinary use. ## Research Focus & Mechanism Overview ### Molecular Identity ### What does the Snap8 sequence tell me? Read left to right, the sequence is two glutamic acid residues, a methionine, a glutamine, two arginines, an alanine and an aspartic acid. The Ac- at the front means the N-terminus carries an acetyl group in place of a free amine, and the -NH2 at the end means the C-terminus is amidated instead of a free carboxylic acid. Both end modifications are common in synthetic peptide chemistry and tend to improve a peptide’s stability against enzymes that attack from either end. A different length, order or terminal capping describes a different compound. ### Which record is used as the reference identity? PubChem holds more than one deposited record for this peptide, and the structure or formula shown differs slightly between them. The record linked to CAS 868844-74-0 (CID 76283482) is used here because its sequence and formula match the conventional Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 structure. The exact monoisotopic mass is not published in that record, so none is stated here. Reference identity comes from chemical records, while lot identity comes from lot-specific analytical documentation. Those are two different things, and a name printed on a vial does not replace the second. ### Is Snap8 the same as Argireline? No. Argireline is a related, shorter six-residue peptide, Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2. Snap8 extends that sequence by two residues, alanine and aspartic acid, giving a distinct eight-residue compound with its own formula, weight and CAS registration. The two share a design lineage but should not be treated as interchangeable. Naming conventions for this class of peptide also vary between databases and suppliers, so a name alone should not be taken as confirming identity. ### Snap8 vs. GHK-Cu at a Glance Attribute: Snap8: GHK-Cu Molecular identity: Synthetic linear octapeptide, Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (CAS 868844-74-0): Copper(II) complex of the tripeptide Gly-His-Lys Structural class: Acetylated, amidated 8-residue synthetic peptide: Metal-coordinated tripeptide complex Chemical identity: 8 amino acids; C41H70N16O16S; 1075.2 g/mol: 3 amino acids plus a coordinated copper(II) ion; distinct formula and weight Research context: Designed around a proposed SNARE-complex, SNAP-25-related interaction: Studied in a separate literature on copper-peptide signaling The two are structurally and mechanistically unrelated, and the table does not rank them. ### SNAP-25 and the Proposed Mechanism ### What is SNAP-25, and how does Snap8 relate to it? SNAP-25 (synaptosomal-associated protein of 25 kDa) is a well-characterized full-length protein. Together with syntaxin-1 and VAMP/synaptobrevin it forms the core SNARE complex behind vesicle docking and membrane fusion. Snap8 corresponds to a short stretch of the SNAP-25 sequence, near its N-terminal region. The design premise is that a free-standing peptide of this kind might occupy a position within SNARE assembly and interfere with its normal formation. That is a structural and competitive hypothesis. Snap8 does not enzymatically cleave SNAP-25, does not replace it, and is not shown to inhibit it directly. ### How settled is the mechanism? SNAP-25 and the SNARE complex are well characterized in cell biology generally. What is less established is an extensive, independent body of biochemical work testing Snap8 itself against that system. Treat the SNARE-interference idea as the working hypothesis the peptide was designed around, not as a demonstrated mechanism in every laboratory model. ### What questions can a lab ask with it? - Does the peptide affect SNARE-complex assembly in a defined in vitro system? - How does it compare with the six-residue Argireline sequence in the same assay? - Which chemical form and counterion was used, and does it match the lot in hand? Veracue does not provide dosing, administration or usage guidance of any kind. ## Quality & Purity Standards ### What to Look for on a Snap8 Certificate of Analysis A certificate of analysis documents one lot, so read it as a set of linked facts. Certificates vary between laboratories and testing programs, so treat this as what a COA may include rather than a fixed checklist. COA item: What it helps establish Lot or batch identifier: Which production run the results describe. It should match the vial. Material name and reference sequence: That the record ties the material to Ac-EEMQRRAD-NH2. Identity confirmation method: How the sequence or identity was confirmed. Analytical method: For example RP-HPLC or ESI-MS. HPLC chromatogram or purity percentage: The reported chromatographic purity and the trace behind it. Mass spectrometry identity data: Whether the observed mass fits the theoretical sequence mass. Testing date and laboratory: How recent the result is and who performed the analysis. Chemical form or counterion: Free peptide, acetate salt or another form, where relevant. Every field above depends on the lot’s own documentation, and Veracue confirms a field only when the lot certificate reports it. Check that the pieces agree with each other. The certificate page explains how to request lot documentation. ### Reading Snap8 Mass Spectrometry Data Molecular weight is not the same figure as the mass-to-charge ratio (m/z) on a mass spectrum. Peptides often ionize into more than one charge state during electrospray ionization, and salts or adducts can shift the observed ion mass away from the calculated neutral weight of 1075.2 g/mol. Mass spectrometry is mainly used to confirm identity, meaning the observed mass matches the theoretical sequence mass within an expected tolerance. Chromatography such as HPLC is what typically establishes purity and composition. No single expected peak is asserted here, because it depends on the instrument, the ionization method and the chemical form used for a given lot. ### Verification Questions, Answered ### How do I confirm that a material is actually Snap8? A name on a label does not establish identity. Start with the documented sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2, CAS 868844-74-0 and the formula C41H70N16O16S. Then cross-check them against that specific lot’s own mass spectrometry and HPLC results. ### What can a product page establish, and what needs lot documentation? A product page can give general reference information such as sequence, formula, weight and CAS. It cannot establish the purity, identity or composition of an individual lot. Treat the lot’s own COA as the operative record for that lot. ### Need lot documentation for Snap8? Ask the Veracue team about available documentation for a specific lot, or review the certificate library. - Request lot documentation - View certificates - Browse the research catalog ## Compliance Notice ### Research Use Only Notice Snap8 is supplied for laboratory research, scientific investigation and analytical characterization only. It is not intended for human or veterinary use, and it is not a drug, dietary supplement, cosmetic or food. This page provides no dosing, administration or usage guidance of any kind. See the Medical Disclaimer and the Terms and Conditions for sitewide policies. ## Questions and answers ### What is Snap8? Snap8 is a synthetic octapeptide, Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2, modeled on a short sequence from SNAP-25, a protein involved in the SNARE membrane-fusion complex. Veracue supplies it for laboratory research only. ### What is the Snap8 sequence? It is Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2, or Ac-EEMQRRAD-NH2 in one-letter code. That is eight amino acid residues with an acetylated N-terminus and an amidated C-terminus. ### What is the molecular weight and formula of Snap8? The molecular weight is 1075.2 g/mol and the formula is C41H70N16O16S, per the PubChem record (CID 76283482) linked to CAS 868844-74-0. ### What is the CAS number for Snap8? The CAS number is 868844-74-0. The exact monoisotopic mass is not published in the linked PubChem record, so none is stated. ### Is Snap8 the same as Argireline? No. Argireline is a related, shorter six-residue peptide, and Snap8 extends that sequence by two residues, alanine and aspartic acid. The result is a distinct eight-residue compound with its own formula, weight and CAS number. ### Is Snap8 related to SNAP-25? Yes, by design. Snap8 is a synthetic peptide corresponding to a short sequence from SNAP-25, developed around the hypothesis that it interacts with SNARE assembly. It is not SNAP-25 itself, not a natural fragment, and does not cleave or replace it. ### How is Snap8 different from GHK-Cu? They are unrelated compounds. Snap8 is a synthetic eight-residue peptide built around a proposed SNARE-complex interaction, while GHK-Cu is a copper(II) complex of the tripeptide Gly-His-Lys. ### Does Snap8 come as a salt or as the free peptide? Some third-party listings describe an acetate salt, but the form of any specific lot is reported on that lot’s documentation. You can request it through the contact page. ### What should a Snap8 COA show? A COA may include the lot identifier, sequence or identity confirmation, HPLC purity data, mass spectrometry identity results, testing date, testing laboratory and chemical form. The lot number should match the vial. ### How should Snap8 mass spectrometry be interpreted? Compare the observed mass-to-charge ratio with the theoretical mass after accounting for charge state and possible adducts. Do not expect a single fixed peak value. ### Does Veracue provide usage instructions for Snap8? No. Snap8 is offered for laboratory research use only, and Veracue does not provide dosing, administration or usage guidance of any kind. More from Veracue Labs: https://veracuelabs.com/llms.txt