# GLP-T Spray

> Research use only. Not for human or veterinary use. Supplied by Veracue Labs.

- Page: https://veracuelabs.com/product/glp-t-spray
- Category: Nasal Sprays
- Sizes and prices in USD: 10 mg at $82.49; 20 mg at $104.49; 30 mg at $131.99; 60 mg at $192.49
- Certificate of analysis: none posted on the page. Request one for a specific lot at https://veracuelabs.com/contact-us.
- Prices are a snapshot from 2026-10-16. The product page shows the current price.

## Overview

GLP-T Spray is a spray-dispensed bottle of GLP-T, a lipidated 39-residue peptide whose chain follows native GIP, with aminoisobutyric acid at positions 2 and 13 and an amidated C-terminus. A C20 diacid is joined to lysine 20 through a linker. It is one molecule engaging both GIP and GLP-1 receptors in assays, so it should not be mistaken for plain GIP. Each bottle holds 45 sprays, in 10, 20, 30 and 60 mg sizes, for laboratory research use only.

## Product Details

### GLP-T Spray at a Glance

Product name: GLP-T Spray
Format: Spray-dispensed bottle, 45 sprays per bottle
Sizes offered: 10 mg, 20 mg, 30 mg and 60 mg

Molecule type: Lipidated synthetic peptide, one defined molecule
Chain: 39 residues following the native GIP sequence
Non-standard residues: Aminoisobutyric acid (Aib) at positions 2 and 13
C-terminus: Amide
Lipid: 1,20-eicosanedioic acid (a C20 fatty diacid) joined to lysine 20 through a linker
Molecular formula: C225H348N48O68
Average mass: About 4813.5 g/mol
Monoisotopic mass: About 4810.52 Da
CAS Registry Number: 2023788-19-2
PubChem CID: 156588324
Receptor targets: GIP receptor and GLP-1 receptor (agonist in receptor assays)
Research designation: Research Use Only

Formula, masses and database numbers are reference values taken from the formula and public chemical databases. They are not measurements of a Veracue lot.

### The Peptide Supplied as GLP-T Spray

GLP-T is a single engineered molecule, not a blend. Its 39-residue chain follows the native GIP sequence, two standard residues are replaced by aminoisobutyric acid, and a fatty diacid hangs from lysine 20. Veracue supplies it in a pump-spray bottle that delivers 45 sprays, labeled with the product name and the size in milligrams, strictly for laboratory research use.

Salt form, purity and other lot-level results are not stated on the site. Documentation can be requested through the contact page.

### Look-Alikes and How They Differ

Several materials sit close to GLP-T in name or structure. The table shows what separates each one and where that difference would appear in analytical data.

Look-alike: What differs: Where it shows

The bare 39-residue chain without its lipid: No C20 diacid or linker on lysine 20: Intact mass reads clearly below about 4.8 kDa
The same chain ending in a free acid: A carboxylic acid at the C-terminus instead of an amide: Mass shifts by roughly 1 Da, so only an accurate mass separates the two
Native GIP: No Aib residues and no lipid: Different formula and a different CAS number
Other lipidated receptor-agonist peptides: A different chain, lipid and linker: Different formula, mass and CAS number
A mixture of separate peptides: GLP-T is one molecule: A single formula and a single CAS number describe the whole material

## Research Focus & Mechanism Overview

### Structure, Piece by Piece

Feature: Position: What it is

Peptide chain: Residues 1 to 39: Follows the native GIP sequence
Aminoisobutyric acid (Aib): Positions 2 and 13: A non-standard residue used in place of a standard one
Lysine side chain: Position 20: The attachment point for the lipid
Linker and C20 fatty diacid: On lysine 20: 1,20-eicosanedioic acid, reached through a linker
C-terminus: Residue 39: Amide

Aib is not one of the twenty standard amino acids. It carries two methyl groups on its alpha carbon, which limits how freely the backbone can turn around that residue, and each one appears in the sequence record as a defined substitution.

### Why does the lipid matter when checking identity?

The diacid is what links the molecule to albumin in biological test systems, and it adds a mass difference that is easy to see in an intact-mass result. Protein content in an assay medium can influence how a lipidated peptide behaves, so it is worth writing down beside the lot record. That is a note on reading results, not a handling or preparation instruction.

### Receptor Targets

Receptor: Name: Behavior in receptor assays

GIPR: Glucose-dependent insulinotropic polypeptide receptor: Engaged as an agonist, with signaling that resembles native GIP
GLP-1R: Glucagon-like peptide-1 receptor: Engaged as an agonist, with cAMP signaling stronger than beta-arrestin recruitment

GLP-T is called a dual agonist because one molecule engages both receptors, but the two are not engaged evenly. Laboratory work published in 2020 described the peptide as imbalanced, occupying GIPR more strongly than GLP-1R, and as biased at GLP-1R, where it drove less receptor internalization than GLP-1 itself.

An assay built on cAMP and one built on beta-arrestin recruitment can therefore rank the same molecule differently, which matters when results from two systems are compared.

### Is the dual receptor profile a property of the whole molecule?

Yes. Activity at both receptors comes from the intact lipidated structure, so a fragment or an altered form should not be assumed to behave the same way in an assay.

### Where This Material Fits in Research

Typical settings are receptor-binding and signaling assays in cultured cells, side-by-side cAMP and beta-arrestin readouts, and analytical method work on lipidated peptides. This is research context only, and Veracue provides no dosing, administration or usage guidance of any kind.

## Quality & Purity Standards

### Reference Masses and Charge States

At roughly 4.8 kDa the peptide rarely appears as one peak at its neutral mass in electrospray MS. It shows up as a series of multiply charged ions, and the table lists calculated m/z values for four of them, derived from the monoisotopic mass of 4810.52 Da with one proton mass added per charge.

Charge state: Calculated m/z

[M+4H]4+: 1203.64
[M+5H]5+: 963.11
[M+6H]6+: 802.76
[M+7H]7+: 688.23

These numbers come from the formula and are not Veracue lot results. Quoted molecular weights for this molecule run from about 4810.5 to 4814 across databases: the lowest matches the monoisotopic value, and the others are rounded forms of the 4813.5 average. A mass at this size is no longer dominated by its lightest isotope peak, so any report should state which convention it follows.

### What Each Analytical Check Can and Cannot Show

Check: What it can show: What it cannot show

Intact-mass MS: Whether the observed mass fits the lipidated molecule, diacid included: Purity, quantity or the order of residues
RP-HPLC: Chromatographic purity under stated conditions: What the main peak actually is
Tandem MS: Fragment evidence for the sequence and for where the lipid sits: How much of the material is that molecule
Amino acid analysis: Net peptide content: The identity of impurities
Counterion analysis: How much of the mass is salt rather than peptide: Peptide quality

A clean chromatogram and a correct intact mass answer different questions. For a lipidated peptide, a result near the mass of the bare chain suggests the diacid is missing and should not be accepted as a match.

### Reading Lot Documentation for a GLP-T Spray Bottle

Documentation can be requested through the contact page for particular products. Before relying on any figure in a document, confirm that it belongs to the lot recorded for your order and that each value names the method behind it.

- A lot identifier that matches your order record
- Formula and expected mass, with the convention stated (monoisotopic or average)
- A purity figure together with the method that produced it
- Observed mass and the charge states used to derive it
- Chemical form or counterion
- Testing laboratory and test date

Results describe the lot that was tested and nothing else, so note the lot identifier beside every experiment that uses the material.

## Compliance Notice

### Research Use Only Notice

GLP-T Spray is sold only to support laboratory research and analytical work. It is not a medicine, supplement, cosmetic or food item, and no human or veterinary use is intended, including any form of administration. Veracue publishes no dosing, administration or usage guidance of any kind, and the science described here is laboratory-level information rather than medical advice. Sitewide policies are set out in the Medical Disclaimer and the Terms and Conditions.

### Qualified Purchasers

Orders are intended for qualified researchers and institutions, who are responsible for working with the material lawfully and within their own institutional rules.

### Packaging Facts

Each bottle holds 45 sprays and carries the product name and size on its label. Anything beyond that, such as chemical form or fill details, is reported in lot documentation rather than inferred from the listing.

## Questions and answers

### How many sprays does one GLP-T Spray bottle hold?

Each bottle holds 45 sprays. The sizes are 10 mg, 20 mg, 30 mg and 60 mg, all sold for laboratory research only.

### What kind of molecule is GLP-T?

A synthetic peptide of 39 residues derived from the GIP chain, carrying aminoisobutyric acid in two places, an amidated end and a C20 fatty diacid on lysine 20. It is one defined molecule, not a mixture.

### Which identifiers pin down GLP-T unambiguously?

Taken together they describe one molecule, and they should agree across any source you check.

### Where are the Aib residues and the lipid located?

Aib occupies positions 2 and 13 of the 39-residue chain, and the C20 fatty diacid is attached to lysine 20 through a linker. The chain itself ends in an amide.

### What masses should a GLP-T result match?

The average mass is about 4813.5 g/mol (4813.53 calculated from the formula) and the monoisotopic mass is about 4810.52 Da. In electrospray MS the 5+ ion is calculated near m/z 963.11 and the 6+ ion near 802.76.

### Why do databases list GLP-T at 4810, 4813 and 4814?

They are rounded forms of two different conventions. The figure near 4810.5 is the monoisotopic mass, while 4813 and 4814 are rounded versions of the average mass.

### Does the dual receptor profile mean GLP-T is two peptides?

No. One lipidated molecule engages both the GIP and GLP-1 receptors in assays, so activity at each receptor belongs to the intact structure.

### Does GLP-T engage GIPR and GLP-1R equally?

No. Laboratory results from 2020 show GIPR occupied more strongly than GLP-1R. At GLP-1R the molecule gave stronger cAMP signaling than beta-arrestin recruitment, so the readout an assay uses changes how it appears.

### Could a C-terminal acid form pass for GLP-T?

Only if mass accuracy is poor. A free acid differs from the amide by roughly 1 Da, so an accurate mass compared with the stated formula is what separates them.

### What does an intact-mass result leave unanswered?

Sequence-scrambled isomers and D-amino-acid forms give the same intact mass as the correct molecule. Fragmentation data and chiral amino acid analysis are needed to rule them out.

### How can I get documentation for a GLP-T Spray lot?

Documentation can be requested through the contact page for particular products. Include the product name and size you ordered so the request reaches the right material.

### Is GLP-T Spray meant for anything beyond laboratory work?

No. It is sold for laboratory research and analysis alone, and no human or veterinary use is intended. Veracue publishes no dosing, administration or usage guidance of any kind.

More from Veracue Labs: https://veracuelabs.com/llms.txt